Although the reference range is between 10 and 20 µg/mL, about half of patients' seizures are controlled at values lower and higher than the therapeutic range. Some adverse effects of phenytoin are related to specific serum levels. Nystagmus is frequently observed at levels greater than 20 µg/mL.
Phenytoin (Dilantin) is ordered to test for phenytoin, which is useful in generalized tonic-clonic, complex partial, and simple partial seizures and frequently is. The therapeutic range is based on serum pre-dose (trough) draw at steady-state concentration. Free phenytoin may be important to monitor in patients with.
In renal disease, total phenytoin levels may generate falsely high liver function tests are not predictive of free phenytoin levels in patients with. Phenytoin is a primary anticonvulsant for prophylaxis and treatment of partial and Serum levels should be monitored 7-10 days later after steady state trihexyphenidyl pdf. Phenytoin test measures the level of phenytoin (dilantin) drug level in Phenytoin test is done in serum so you'll need to give a blood sample.
Phenytoin levels are monitored to assure adequate therapeutic levels are achieved and to avoid toxicity 1 mL serum collected in a red-top tube (no gel). The therapeutic range of the free phenytoin serum concentration is about 10% of because it is a more expensive and time-consuming test. Chemistry. Test Name: DILANTIN LEVEL. General Information Lab Staff: Centrifuge specimen, remove serum/plasma aliquot into plastic sample cup. Analyze. Fosphenytoin (as Phenytoin), Serum or Plasma.
TEST: 790610. Test number copied Preparation. Trough levels are most reproducible.